Yes. Here's what I do for a skull/skull cap.
Skin it, remove the eyes, nose, tongue, and lower jaw if it's not wanted. For a cap, saw where desired.
Place in a container with water. I prefer warm water (about 85* seems to be the ideal) as everything goes more quickly. Some people talk about putting a horse fecal ball or something similar but I don't find it necessary -- there is enough bacteria in the nasal cavity to repopulate the planet.
If it's a horned animal, the horns need to be submerged. Check them at least every other day. For small animals like antelope the sheaths will slip in 2-3 days. Larger animals like Bison will take a week or more.
When the horn sheaths slip, remove them, rinse, wash in Dawn dishwashing liquid and let dry (they'll still stink a little).
For antlered animals, try to keep the antlers above the waterline as much as possible but have all the bone underwater.
Then you just watch it until everything rots off (it really reeks). The general rule is let it rot off -- if you're picking it's not ready to come off yet. The soft tissue will literally liquify and not require
any elbow grease.
Once all the soft tissue is gone, the skull will really stink, will be a little yellow/off white, and will be a little "loose" at the skull sutures. If you soak it too long, the skull will start to fall apart, lose teeth, etc.
Rinse well in water and place in clean water (don't let it dry out).
Next I boil for just a few minutes (to kill the smell primarily). I'm talking 10-30 max.
I boil the horn sheaths for about 5 min in plain water.
I boil the skull itself in water plus Calcium Carbonate (NOT bicarbonate) at a ratio of 1 cup per 20 gallons.
Again rinse in water but don't let it dry.
Finally I wrap it in white paper towel (wad some up and stick it in the eye sockets, etc). Cover the paper towel with 40% hydrogen peroxide and put the whole she-bang in a white trash bag. I'll slosh it around in this for 2-3 days. Don't get any peroxide on the antlers-it'll bleach everything it touches.
It'll look pretty white at this point.
Rinse again in clear water - be sure you're wearing latex gloves at this point because the bone is very porous and will soak up oils from your hands that you'll never get out.
Let dry. It'll continue to whiten as it dries.
I usually apply a thin coat of Krylon Crystal Clear to protect from fingerprint smudges (this is the only "artist-type" coating I've ever found that does not yellow over time.
I get the CaCo3 and H2O2 from Van Dyke's taxidermy supply.
The Krylon you should find at a hardware or art supply store.
here's a bear done about 5 years ago:
these two were done about 2 & 6 years respectively
not the best pic but this was done about 3 years ago