I have a straight grip stainless laminate 358 takedown. Running a 2-7 in leupold QDs on the receiver. I then have a 1.5-4 pistol scope in leupold weaver style QDs mounted on the barrel. My thinking is to sight in the barrel mounted scope with a close range heavy thumper and standard load for the 2x7. Accuracy has been great. Point of impact wobbles about 1/2 inch right to left after takedown and reassemble. The thing I like the best is ease of cleaning and that was the main reason I bought it.
My first BLR T/D is in 308 Winchester has a 2-7x33mm Leupold "Rifleman" scope
receiver mounted on Warne QD mounts. It really likes the Nosler factory loaded 165 grain "Accubond" ammo so that's what I feed it. The gurus warned me to mount a scout scope on the barrel cause I'd have POI "wandering" problems when disassembling/reassembling if I receiver mounted the scope. Trouble is I hate scout scopes. My POI wander is about 1/2" @ 100 yards each time I completely disassemble the gun into 3 pieces & reassemble the gun. That's well within hunting accuracy requirements as I use the gun for deer, moose & elk at 300 yards or less. 1/2 MOA is irrelevant under those circumstances.
My latest BLR T/D is a 450 marlin & I set it up the same way except with Burris QD rings. Have yet to range test it.