I often shot as many as a hundred rounds through either of my 22-250's between bore scrubbing. I never saw a loss of accuracy, when shooting ground squirrels.
Is there a huge difference in if the bullets are moly coated or not?
There is a thread in reloading game rifles where this subject is presently being discussed. If you read this, you will know as much as I presently do about moly.
https://www.24hourcampfire.com/ubbthreads...p;vc=1&nt=5 How long should I wait in between shots when target shooting?
There are a lot of answers to this question. Basically one must ask, "How long do I want my barrel to last?". Or to put it another way, "How many rounds do I expect to shoot from this barrel before replacing it?"
Some guys never let the barrel on a 22-250 get warm to the touch, they might get 2000 to 3000 rounds out of that barrel. Some fellows burn over 100 rds an hour at a prairie dog town, and you could fry eggs on their rifle barrel. That person will probably have to replace the barrel at 750 to 1000 rounds.
Any load that pushes a bullet to 4100 FPS is a pretty intense load. It will be hard on the throat of the barrel. I have been very happy shooting 60 gr bullets at 3600 to 3650 fps and got pretty decent barrel life.
But back to the point of your question, I do not worry to much about waiting between shots until I have fired the third one. After three rounds, even a varmint weight barrel will feel a bit warm to the touch.
After three rounds, I like to set that rifle to the side for at least ten minutes to cool, perhaps longer, if it is 105 degrees out and the rifle is sitting in direct sunshine. After letting the barrel cool a bit, I will only shoot a couple of rounds or maybe one, before letting it cool again. It depends on how warm the barrel feels in my hand. I try to never let the barrel get so hot that I can not hold it in my hand indefinitely.
I would really suggest that you check out the reloading forums. For the price of a few boxes of shells, you can get all the tools needed to assemble your own ammunition. One can then enjoy the time spent reloading as well as have a lot more ammo to shoot for the same amount of money.
If space is a problem, Lee makes a hand held press. It works well. For many years, I kept everything I needed to reload for three different rifles in a boot box under my bed. I did all my reloading on the coffee table with the assistance of my small children.