Physics, statistics, and Excel is how this mess got started. Every combination has its own set of concessions and the importance (or lack of) is up to the guy yanking the trigger. Across the SA chamberings, 260 won for ME everytime, and 7 RM is my thumper of choice. Albeit it the newbie in the rack and will probably see the least use. But 162 Amax at 3,000 FPS does give some warm and fuzzy....