Hydrocodone and tramadol make me itch furiously; big doses of benedryl help some, but it's still like full body poison ivy! My neurologist put me on Nucenta, which is tapentadol, and it works fairly well to relieve some pain without me clawing my hide bloody. The hydro is also a bowel plugger upper as already mentioned, best take some laxative with it, straining to go with burnt skin would be hellish. It was pretty bad after back surgery a few years ago.
