Whenever this subject comes up I always recommend reading these two articles as they specifically address the differences between the .44 Magnum and .45 Colt with a little discussion of the .41 Magnum tossed in.

http://www.customsixguns.com/writings/heavyweight_bullets.htm

http://www.customsixguns.com/writings/dissolving_the_myth.htm

Gunnery, gunnery, gunnery.
Hit the target, all else is twaddle!