I settled on 210/215 grain bullets and 2400 powder in the .41 Magnum many years ago. Jacketed bullets get 18/2400, std primers; hard cast lead gets 17.5/2400, std primers.

These loads have been superbly accurate in my three Model 57 S&W revolvers. As a caution, do not down load 2400, as it's at its best with full magnum loads.