I'm running a Swarovski 3-9x36 in Warne detachable rings. A 3-9x40 would have been nice, but the Swaro was unemployed at the time and I feel the quality of the glass makes up for any dimmer image...looks bright as can be to me!
I'd stay away from any of the cheaper Chinese-made scopes; they may be fine on your .22-250, but the .375's recoil can shake things up a bit. The last thing you need on the "hunt of a lifetime" is a loose reticle!