If your scope has the Varmint Hunters reticle, using a 100 TTSX at 3700 fps, just sight it in at 300 yards. It won't rise more that 2 MOA at the high point, and gives you a point blank hold out to 375 yards.
Using the large triangle setting, your actual trajectory fits the reticle subtension "minute of coues deer" out 500 yards no problem.
Range ActualDrop Subtension
400 Yards 1.74 MOA 1.81 MOA
500 Yards 3.79 MOA 4.13 MOA
625 Yards 6.85 MOA 7.02 MOA
I used the VH Reticle on my 6.5 WSM to take a couple of good coues deer in Mexico before things go dicey down there. One at 375 yards and one at 480. The reticle worked great.
