I have been watching this thread since it's inception, waiting to see if anyone would actually give what I consider to be THE best answer. A couple have touched upon it, but nobody has really put it into concise terms.

The answer is (drumroll please):

Shoot the deer where the scapula and humerus meet (Or just slightly behind it). Break that joint and it's good night Irene every time. It will produce a bang flop (with quick death, no running, struggling, or getting up) more reliably than any other shot placement, including head, neck, heart or high shoulder.....