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I prefer 225 grains if the case is big enough to boot it out decently.



The Barnes pictured above is the first Barnes copper I ever fired at an animal and it 'shouldered' a big bull before coming to rest in a blister under the skin. That was with a 340 Weatherby at somewhat under 200 yards. Normally I, and many moose hunters I think, use 250 grains when using lead-cored in their 338s. Dropping a step to 225 seems about right on these big deer. In the same way, the 180 is easily the most common weight in the 300 mags for moose up this way, so the 165 mono seems about right.

But again, my initial thought if this was me, neither load seems lacking and I would be considering what I'd rather carry through swamp and over dale, and which I would prefer to swing and shoot in the brush.