In my old Remington 725 .280 Rem., for years I've used the 140 grs and 160 grs Nosler Partitions, and the 139 grs Hornady Interlock bullets on Elk, Mule Deer, Blacktail deer, antelope, and Black bear. They have always performed well for me.
Guess I'll stick with 'em.
L.W.