Wow! You guys get pretty complicated about the whole thing. Looks like fun and maybe someday I'll join in. But for now....I've used the same load in my Guide Gun (and those of 2 friends) for about 20 years now: 400 grain Speer flat nose over 54 or 55 grains of Varget in Starline cases with CCI 200 primers. It's not what I'd call a pleasant load to shoot, but I don't shoot it that much. It does shoot flat enough that, with a 100 yard zero, the POI is pretty close to the point of the bottom coarse section of my duplex reticle at 200 yards (1-4 Leupold Shotgun-Muzzle Loader scope with coarse duplex reticle) with the scope at 4X. It has killed a lot of deer very dead.
