I've used bullets up to 200 grains in the .30-06 for antelope, partly due to minimal wind-drift and partly due to shooting up less of the great meat, if by chance the bullet does end up in or near a shoulder. In fact I used 200-grain Nosler Partitions years ago, before all the present high-BC bullets had appeared, and they worked great.

“Montana seems to me to be what a small boy would think Texas is like from hearing Texans.”
John Steinbeck