I had loaded some 30-06 and 375 Ruger rounds with 4451 a while back and finally got to the range this morning. Based on this limited experience, I am sold on 4451. Accuracy with 165 Hornady's in the 06 and 300gr. A-Frames in the 375 was outstanding. Did not chrono them yet. I had always used H-4350 in these loads before with good results.

Think I'll stock up on the new stuff.