I remember a tale from an outdoor writer back in the day; I don't know if it was Ross Seyfried or another,
IIRC.
Jack O'Conner was the writer. The overalls were dyed a " bilous green" and the farmer carried the 270 while plowing and shot varmints on a regular basis with it.
I would take the 270 but use premium ammo probably 130 TSX or 150 Partitions. As others noted anatomy and shot placement are the keys to talking game not the cartridge.
So many people get a magnum for an African hunt that they are not familiar with and don't shoot as well as their tried and true deer rifle.