I did a 300 WSM as a "one rifle" for a while, antelope to elk. Of course it works, but I found the 308, 270 or 30-06 a better choice for a "one rifle" because they can be built lighter without kicking the snot out of you. They all work.
“Perfection is Achieved Not When There Is Nothing More to Add, But When There Is Nothing Left to Take Away” Antoine de Saint-Exupery
