If you are not careful with N110 it will blow sabots. It may require more tinkering but if you are happy with lower speed loads its great. Ive seen 1 or 2 guys shooting loads as high as 37gr but most cant get over around 33gr before sabots start failing. Use a wad under the sabot. 4198, Reloder7 and N120 are all good powders for the 45cal and sabots. The load i want to try is around 55gr or possibly less of N120 and the Fury 250gr 40cal. The Fury 250 is shorter than the Pittman 225gr but it has a lower BC. Its also less than half the price and bonded.
N120 was claimed to be somewhat temp sensitive with a 200gr. Fps difference as temps drop was more than 4198. My guess is the heavier bullet will improve the milder N120 loads and even 4198. You will get a better burn with the heavier bullet and give up very little speed.
