H110 has been my standard for jacketed .44 loads for a couple of decades. An article on primers in the 2015 Hodgdon Annual revealed that H110 did very well with standard LRs, though cold weather might change that. I use them all the time with no issues at all. Certainly they’re fine for 2400 as well as faster powders.
If you have a Hodgdon manual, take a gander at the data for 240gr Noslers and H110. The staring load is only slightly slower than the max load, but the pressure is much lower.
To be clear... you just recommended subbing in Large Rifle primers?
