Penetration is but one factor in evaluating the performance of a round. The dia of the wound channel is also critical. A high velocity bullet is going to disrupt more tissue than a low velocity bullet, and once you get consistant exits, more penetration is not needed.

Years ago a sent some .475" 460 gr bullets to a guy who tested them at the Linebaugh seminar. He launched them out of a lowly 480 at a mere 1100 fps, and penetrated 38" of wet newsprint. I could conclude from that that a 480 is 83% as good as a 416 Rigby, and that your 500 linebaugh is 10% more powerful than a 416. But penetration isn't everything, and I don't hunt wet newsprint.