Be careful. 46gr varget....that would leave primers laying in the action in my FTR rifle. 45 will cause an occassional pierced primer and cause cases to stick. 44 runs good, real good. I have a salvage with another min spec chamber thing will not even start shooting to 45.5 and humms them at 46.5. That said I have never seen a 308 that would not shoot somewhere between 43 and about 47. I tell friends that if your 308 will not shoot with a 168 VLD and 45ish grains of Varget it is broke....but it is important to work up.