If it were me I'd use a 140 gr accubond & enough imr 7828 to make it do 3400 across my chronograph. Before a thief relieved me of my STW I ran a 140 gr partition at 3400 on deer. Today I'd pick the accubond. No need for anything heavier than a 140 accubond, I never understood the logic of taking a fast round then slowing it down with a heavy bullet on something like deer, the tough 140's will shoot through them anyways, no need for extra penetration.