Interesting subject,especially if you're a 243 fan.I've never hunted elk with a 243 but I believe if you keep your shots under 200yds. and use a well constructed bullet i believe it's definately possible as long as you wait for the proper shot to present it's self {broadside shot}

I love the 243 for whitetails.I guess there's a couple ways to look at the senario: if you're going on an elk hunt once in a life time or once every couple of years and you dropped $6k on the hunt and you might not get the opportunity to get close enough or the perfect shot doesn't present itself then i'd want more gun than a 243.But if you live in an area where the elk live and you get the opportunity to hunt them once a week where you can be patient to wait for the right shot then i'd take the 243.

I'd take a well place shot from a 243 rather than a bad shot from a 300 win. mag.