Varget is a good powder no doubt. Doesn't do very well with a powder measure. Reloader 15 is another powder that is right in line with Varget. Seems like I can get a little more velocity out of Reloader 15. The powder I am taking a liking to is IMR 8208XBR. Shoots really good in my 250.

H380 is a good powder for the 250 and its really easy to find a load with. But I tend to stay away from in the summer. Other good powders to mention are Ramshot Big Game, Accurate 2700, IMR 4064, IMR 4007SSC.