Tanner, I've been a devout .375 fan for many years; going back to the time when Elmer Keith revived interest in it and Ruger came out with the #1 in that caliber.
My beat-up old pet .375 is an Interarms Whitworth fitted with a just-as-old Zeiss 1.5-6 x 42 scope.
My favorite load is the Sierra Game King 300-grain boattail and 75 grains of IMR 4350 for just under 2,500 fps, which is Elmer's old load and still shoots into cloverleafs at 100 yards.
Years ago I had the privilege of reviewing Keith's original correspondence with Sierra when they partnered with him in developing that particular bullet.
I've killed everything with it from antelope to elk, and I loaned it out to friend for moose. It's always done just what the old man said it would do, and you can "eat right down to the hole."