Anyone ever used this combo with success on deer?

Good to be loading some for an older friend ( retired Marine) who has just had shoulder surgery, and also retinal surgery on his right eye recently...

Doc told him to retire his 30/06 and take up golf... he already golfs anyway, but his son picked him up a 243 Weatherby Vanguard...

he shot some of my handloads and liked them... now the question is if the bullet is up to the task... I am sure it is, but that is speculation... proof is even better... grin

if that doesn't work, maybe I can talk him into shooting a TTSX in 80 or 85 grains... or my second choice was the 85 gr HP Sierra...