I agree with Tman about them being like a bomb on chucks. I have shot the HP variety of the 75's for about 15 years. A couple of things they do well. One they seem to give chucks flying lessons, gut them and dismember them, all in one shot.

I would not hesitate shooting deer with the load using lung shots or neck shots. After all, in my young adult years, I shot quite a few deer with a 22 LR. Never lost a one.