I ran across this guy doing a google search for ballistics and loads, etc. His site is Terminal Ballistics Research and he writes as if his is the authority on all fact. Here is his comment in regard to the 250-3000 Savage. I had never heard this before. Have any of you? (see his quote below).

The .250-3000 became extremely popular for a time, then gradually lost favor. Hunters, not only in the U.S but throughout the world adopted the Savage for its advertised virtues but soon found the cartridge wanting. The lightly constructed 87 grain factory load would sometimes suffer bullet blow up on impact and fail to penetrate the onside muscle and bone of a variety of deer species. Wounding was often both narrow and shallow and game animals would run after being hit with well placed shots. To add to the frustration, many hunters found the light recoiling, fast handling and highly accurate Savage rifle extremely nice to use. Hunters were loathe to part with the Savage rifle but loathe to use the cartridge on deer.

Eventually, a 100 grain load was created for the .250 but by this time, the cartridge already had a bad rap. Nevertheless, a small portion of hunters continued to enjoy using the .250 on light bodied game, favoring the light recoil of the .250 combined with the desirable qualities of the Savage 99 rifle. As can be expected, the .250 was a great cartridge for training young hunters and it is in this last role that the .250 Savage has survived through to the present.