I've a 99H in 250 and this rifle seems partial to Reloader powders, 19 for 100 grain bullets and 15 for the 85-87 grainers. 4350 has worked well in other rifles with 100grs. and I don't know why 4895 wouldn't work well w/either bullet weight. Might not give the most velocity but should be more than accurate enough! My 2 cents...
Cheers

"The more I am around people the better I like my dog." Mark Twain