Absolutely it can. It will work with the inlines and with 209s. It'll also work with traditionals and musket caps or #11 caps. And, it is all that works with flintlocks. I do that with each every year.
FFFg in a .50 caliber will be JUST fine. FFg will work, too, if that's what you can find.
America needs to understand that our troops are not 'disposable'. Each represents a family; Fathers, Mothers, Sons, Daughters, Cousins, Uncles, Aunts... Our Citizens are our most valuable treasure; we waste far too many.