I can guarantee you a Rem 725 rebarreled to .260 with 140 gr. Corelokts will kill a cow elk at @ 150 yds drt, wolf at 40 drt, and several caribou drt at 200 - 400 yds.
Unless you pecker shoot one first. But that WILL slow 'em down!
Allow for windage....not to mention remembering to use the range-finder...