I'm a bit skeptical of specialty loads for self defense. All handguns are pretty anemic and there's no way to make a handgun into a rifle regardless of the load. I'm most comfortable with loads that have established gunfight records in law enforcement. These would include Federal HST, Winchester Ranger T-Series, Speer Gold Dot and to a lesser extent Remington Golden Saber. Cor-Bon DPX also has a good track record although they aren't used as much by LEO's.
