Started my son on a 308 pushing a 125 NBT at a whopping 1800fps......every deer he pointed it at and pulled the trigger on died......ranges were limited to 100 yds and all deer (5 over three years) died within 100 yds........the interlock is a CNC bullet......it will work fine on deer at 100 yds..... hint......its more WHERE you shoot em at rather than WHAT you shoot em with..........