how big an animal will you be hunting? If elk are on the list, that makes the 243 less than ideal and 260 questionable IMO.

For target shooting at LR, it can be hard to see misses hit dirt with a 243.

I have a LR rifle in all 4 cartridges. The 7-08 with berger 168 hunting VLDs is my favorite, great BC and you can see misses. I've had a couple of 260s, currently have a Tikka T3 Sporter, and I compete with a dpms 260, great cartridge. The 308 is a Kimber Tactical and I love it, but the BC really kills it past 800 yards. My 243 is an ackley and is a tackdriver but I can't see dirt fly at LR except under great conditions.

My opinion would be 260 or 7-08.