With the bullets we have today, this seems a foolish discussion. It's no trouble at all to put together a 30-06 round with very low recoil and good for 300 yards if need be.

I've torn both rotor cuffs and know what bad shoulders are. Full power 130 grain TTSXs are deer killers deluxe. I doubt that anyone could tell the difference on game if you back them down 10% or so, but the recoil drops back in a hurry.