The first and last 225 NBT I used in my 358 Winchester blew up on a red fox, scattering the jacket just beyond the animal in a ball of fur as well as lead particles (and fox bits) all around on the snow. Fox was very dead, but so was the bullet. Most NBTs I've used have worked well; not sure I would trust a bullet so heavy which comes apart on an animal so light.

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Sometimes, the air you 'let in'matters less than the air you 'let out'.