One of the strong advocates of the .22 cal. on deer once admitted thinking about this very thing.. Doubt he remembers, but the poor blood trail issue was the crux of the issue.. think this would have happened with a .270??
.22's are deadly, but as an old W. VA. mountaineer once told me with the . 22 centerfires, you loose one every so often.. This guy had not shot dozens of deer, or hundreds, but probably thousands..When he spoke, I listened..
