I fully concur with he vast majority of responses.
In the last 10 years in Canada, our "little" .243, a savage model 11, cheap as chips package, has accounted for 2-3 WT deer every season. Big bucks or does, it doesn't matter.
We've mostly used factory ammunition through it. Blue box 100gr, Fusion 95gr, superformance 95gr SST, 85gr TSX. Does not matter.
Don't recall any DRT, as we hunt for meat, so try to stay in the boiler room. Only 1 ran more than the typical 50 yard death run, & it was hit to far back (Liver), but even it only an 150 yards.
