AZ clues and antelope can take long shots, for me 400 is not unusual. Wind is always more important than range which is easy now with lasers. I have experience with Nosler Accubond and Barnes TTSX but not e-tip. As an example with the Accubond, at the velocities I get the 10 mph drift at 400 is reduced by 3" going from 100gr to 140gr which to me is a material improvement when I am guessing what the wind is doing across a canyon or out there in the grasslands. I would not even look at an 85 gr for long shots should you need one.
I would not hunt Moose/Grizzly with a 270.
