I don't get into it as deeply as you fellas do, but I shoot 210gr RNFP hard cast over a full load of trail boss.
I added a 3 screw Blackhawk to the collection a couple months back and finally took it out this weekend. I started out shooting at 1/2 gallon juice cans, then went to regular tin cans and finally, empty .22 boxes at 25 yards; nocking them down with regular rhythm.
I have been amazed at the ease of accuracy in every .41 I shoot.
Has anyone ever have a bad one?