Not a gun writer or bear guide, but, if it's what I had to use I'd stoke it with 140 gr partitions with a 1.5-5 Leopold up top and practice, practice, practice!
I shot an "easy-to-kill" medium sized bull moose years ago...with my Swede..distance around 150 yards.. 2 140 A-Frames, 2 140 Partitions. The all four shots landed basically broadside catching the muscles of the legs as well as the lungs over a period of time that it took to reacquire the target among a small group of animals. The animal finally keeled over when a buddy snuck in and poked a 180 Core-lokt (30-06) which ventilated the lungs and both side of the animal. The best penetration I got was the Partitons, which were against the hide when they stopped; the A-Frames stuck in the muscle mass of the offside leg. Having had a much smaller animal, a small DLP bear 'catch' (and hold) a 12 gauge Brenneke slug , broadside, at under 30 yards, I'm not a big fan of playing bullet/rifle limbo. Not saying it can't be done....