The 250 AB's work very well on big game--I've taken quite a few animals with them in both North America and Africa, at 2650 fps or so from either my 9.3x62 or 9.3 B-S. Their BC is high enough that they shoot a lot flatter than most hunters would guess, since so many assume the 9.3's are "timber" rounds. At that velocity their trajectory is very similar to the standard 180-grain .30-06 load, and I've had no trouble taking game out to 300+ yards, and wouldn't hesitate at 400, where the retained velocity is still right around 2000 fps.
