Not an expert, but, based on the general toughness of Leupolds and the fact that it only weighs 8oz., I believe it'll do well. Especially since the .375 offers more of a shove than a .300 or .338 magnum. I just put M8 3x on mine. Plenty of power for anything you'll shoot with a .375.


"Civilized men are more discourteous than savages because they know they can be impolite without having their skulls split, as a general thing."
Robert E. Howard