I carry a Skeleton Ruger in .300 Win Mag topped with a VX-3 3.5-10x40 duplex
Load is 72 gr RL22 over a 180 TTSX

My wife and kids shoot 140 grain accubonds with a stiff load of Varget out of a couple different 7mm-08s. One is a Ruger Frontier with a 16.5" barrel, the other a Savage Axis...both are topped with Vari-X IIs.

My backup rifle this year is another Skeleton Ruger that was a .30-06 but I sent it off and had it re-bored and chambered to .35 Whelen. Tagged out this year on elk so likely won't bring out the Whelen until spring bear.