I have had awful good luck with the 100 grain Hornady out of a 'Bob, but if I were travelling long distances and paying piles of money to hunt, I would take my time and find out which one of the following three bullets shot best out of my rifles.

110 grain Accubond
100 grain TSX
100 grain partition

any one of the three will make a deer of any stripe, bad sick.

"The number one problem with America is, a whole lot of people need shot, and nobody is shooting them."
-Master Chief Hershel Davis