I live in Homosassa and the best place to go fishing is the area between Homosassa and Yankee town to the north. There are plenty of good motels on US 19 [ the main drag] and plenty of access points to the gulf. If you are bringing a boat, there are good free boat ramps on the Homosassa and Crystal river and up by yankeetown and Inglis. Redfish, Trout, Snapper, and others are plentiful and easy to catch.
Go to Myfwc.com and you can find out everything you need to know.
Medium tackle is plenty fine. D.O.A shrimp work well as does live bait.