Back when I was prepping for my first Africa trip, I shot a couple of desert mule deer (about the size of your average midwest whitetail) and a couple of big bull elk using 260 AccuBonds in my .375 H&H. All were one-shot kills, with minimal meat damage, and only the two used on mule deer exited. They would also reliably put five shots into one inch at 100 yards, if I did my part.
