More is better considering the defense ammo available today...but i am still partial to a Glock 22.
It's an excellent round and handgun. Larger hole and more ft. lbs. energy on target cannot be bad, and mag capacity for the same platform is just a hair behind 9mm. If you can handle the recoil exactly as well as you can 9mm out of the Glock 17, it's a great choice.
For me, I notice the recoil difference, and would require more live-fire range time to narrow the gap (round to round) between the 17 and the 22, so (not being able to afford the thousand rounds a week I'd need), I stick with the 17.
