I killed a decent 5x5 bull with a 7mm rem mag shooting 145 LRX's at 3225 MV this year. 100 yds broadside with two shots through the shoulder, both were complete pass throughs. I found one broken off petal when cleaning him.

Last year I used the same load on a 6x6. Again two bullets complete pass throughs but that one was 375 yds.

I've yet to recover a bullet and all four shots penetrated both shoulders of mature bull elk. Neither really needed a second shot but I like a second if they're still standing, at least with elk.