My mentor when I was learning to bow hunt taught me to aim for the exit (wound). I learned that it translates well to rifles too. If the deer is quartered to or away, aim so that the bullet/arrow passes through the vitals between the shoulders. With a rifle, high and tight behind/in front of the shoulder has given me the most DRT's. I learned the hard way that aiming behind the shoulder on deer even slightly quartered to you gives you an exit through the paunch. If the deer is quartered away hard, I either wait for a better shot or let them walk.
Exactly how I was taught along with understanding the anatomy and how I have taught my son.
